DigiM works with clients to characterize, predict and optimize the pharmacokinetics of active pharmaceutical ingredient, or the movement of the drug through the body, using 3D imaging, image-based Quality by Design (QbD) and microstructure physical simulation.

Based on Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) and Micro-Computed X-Ray Tomography (MicroCT), DigiM provides a unique 3D high resolution imaging solution to obtain an effective microstructure evaluation of drug release profiles.
By visualizing the microstructures of drug products using DigiM’s technique, our clients are able to see the difference in release profiles between a generic drug and a name brand drug. This insight has been crucial for our clients in achieving well-informed marketing strategies in a cost-effective manner.

DigiM has the potential to assist on broader pharmacokinetic applications including: controlled pharmacokinetics, chemistry, manufacturing and control manipulation, and manufacturing quality assurance.


Qualitative and Quantitative Comparison

Brand Name (Left) vs. Generic (Right)

BrandNameVGenericComparison



Pellet Reconstruction with High Resolution 3D X-Ray Microscope