Publications

Publications

DigiM pioneers in 3D microscopic imaging, image analytics, and image-based simulation, with a track-record of joint publications and presentations with our elite customers.

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  1. R. Ho, Y. Shin, S. Zhang, A. Zhu, P. Kumar, H. Goyal. Advanced image analytics to study powder mixing in a novel laboratory scale agitated filter dryer. Powder Technology (417:118273) (2023). DOI.
  2. Y. Pu, L. Ma, B. Dear, A. Zhu, J. Li, S. Zhang, W. Shi. Understanding the impact of microstructures on reconstitution and drying kinetics of lyophilized cake using X-ray Microscopy and image-based simulation. Journal of Pharmaceutical Sciences (2023). DOI. 
  3. Y. Suleiman, N. May, M. Zhang, A. Zhu, S. Zhang, J. McCutcheon, S. Shahbazmohamadi. In-situ 3D X-ray Tomography and Analysis of Reverse Osmosis Membranes Under Compaction. Microscopy and Microanalysis (28:S1) (2022) 270-271. DOI.
  4. A. Clark, R. Wang, Y. Qin, Y. Wang, A. Zhu, J. Lomeo, Q. Bao, D. Burgess, J. Chen, B.  Qin, Y. Zou, S. Zhang. Assessing microstructural critical quality attributes in PLGA microspheres by FIB-SEM analytics. Journal of Controlled Release (349: 7) (2022). DOI. With the FDA and UCONN.
  5. W. Jia, P. Yawman, K.M. Pandya, K. Sluga, T. Ng, D. Kou, K. Nagapudi, P.E. Luner, A. Zhu, S. Zhang, H.H. Hou. Assessing the Interrelationship of Microstructure, Properties, Drug Release Performance, and Preparation Process for Amorphous Solid Dispersions Via Noninvasive Imaging Analytics and Material Characterization. Pharmaceutical Research (2022). Available online: DOI. With Genentech.
  6. A. Zhu, C. Mao, P. E. Lunar, J. Lomeo, C. So, S. Marchal, S. Zhang. Investigation of Quantitative X-ray Microscopy for Assessment of API and Excipient Microstructure Evolution in Solid Dosage Processing, The American Association of Pharmaceutical Scientist PharmSciTech Journal (23:117) (2022). Available online. DOI. With Genentech. Highlighted in Pharma Excipients article.
  7. T. Yeoh, L. Ma, A.Z. Badruddoza, J. Shah, S. Zhang. Semisolid Pharmaceutical Product Characterization Using Non-invasive X-ray Microscopy and AI-Based Image Analytics, The American Association of Pharmaceutical Scientists Journal (24) (2022) p. 24-46. DOI. With Pfizer.
  8. Y. Chen, D. Moseon, C. Richard, M. Swinney, S. Horava, K. Oucherif, A. Cox, E. Hawkins, Y. Li, D. DeNeve, J. Lomeo, A. Zhu, L. Lyle, E. Munson, L. Taylor, K. Park, Y. Yeo. Development of hot-melt extruded drug/polymer matrices for sustained delivery of meloxicam, Journal of Controlled Release (342) (2022) p. 189-200. DOI. With Eli Lilly.
  9. S. Zhang, K. Nagapudi, M. Shen, J. Lomeo, Y. Qin, A. Zhu, P. Nayak, D. Chang, R. Hannoush. Release Mechanisms and Practical Percolation Threshold for Long-acting Biodegradable Implants: An Image to Simulation Study, Journal of Pharmaceutical Sciences (2021). DOI.  With Genentech.
  10. J. Gamble, M. Tobyn, S. Zhang, A. Zhu, J. Salplachta, J. Matula, T. Zikmund, J. Kaiser, P. Oberta. Characterization of the Morphological Nature of the Hollow Spray Dried Dispersion Particles Using X-ray Submicron-Computed Tomography, AAPS PharmSciTech (2021) 23-40. DOI. With BMS. 
  11. S. Zhang, P. Stroud, A. Zhu, M. Johnson, J. Lomeo, C. Burcham, J. Hinds, K. Blakely, M. Walworth. Characterizing the Impact of Spray Dried Particle Morphology on Tablet Dissolution Using Quantitative X-Ray Microscopy, European Journal of Pharmaceutical Sciences (165) (2021) 105921. DOI. With Eli Lilly. 
  12. Z. Liu, L. Li, S. Zhang, J. Lomeo, A. Zhu, J. Chen, S. Barrett, A. Koynov, S. Forster, P. Wuelfing, W. Xu. Correlative Image-Based Release Prediction and 3D Microstructure Characterization for a Long Acting Parenteral Implant, Pharmaceutical Research (2021). DOI. With Merck. 
  13. S. Zhang, J. Lomeo. Cloud-based image management solutions for digital transformation of drug product development, Microscopy & Microanalysis 27 (S1) (2021) 296-297. DOI.
  14. S. Horava, J. Lomeo, M. Shen, R. Ayyar, K. Eddy, S. Zhang, M. Swinney. Evaluating API Release Performance from Controlled Release Polymer Matrices with Microstructure Imaging and Image-based Prediction Models, Talk presented at CRS 2021 Virtual Annual Meeting, 2021 Jul 25-29; Virtual. Eli Lilly talk featuring DigiM’s analysis.
  15. I. Terzic, M. Staal, A. Doornbos, I. Kok, K. Staal, J. Visscher, A. Funhoff, T. Nguyen, W. Vos, P. V. Midwoud, R. Steendam. Next generation bioresorbable contraceptive implants, Talk presented at CRS 2021 Virtual Annual Meeting, 2021 Jul 25-29; Virtual. Innocore talk featuring DigiM’s analysis.
  16. M. Shen, Y. Wang, S. Zhang, B. Qin, Q. Bao, D. Burgess. Characterization of the Stability of PLGA Microspheres Using Image-based Key Performance Attributes and Release Prediction, Poster presented at CRS 2021 Virtual Annual Meeting, 2021 Jul 25-29; Virtual.
  17. K. Nagapudi, A. Zhu, D. Chang, J. Lomeo, K. Rajagopal, R. Hannoush, S. Zhang. Microstructure, quality, and release performance characterization of long-acting polymer implant formulations with X-ray microscopy and quantitative AI analytics, Journal of Pharmaceutical Sciences. (2021). DOI. With Genentech.
  18. S. Zhang, G. Byrne. Characterization of transport mechanisms for controlled release polymer membranes using focused ion beam scanning electron microscopy image-based modelling, Journal of Drug Delivery Science and Technology. 60 (2021). DOI. With Merck.
  19. S. Zhang, A. Koynov, J. Lomeo. Computer Aided Drug Formulation Design with Image-Based Microstructure Modeling, Poster presented at: AIChE Annual Meeting, 2020 Nov 16-20; Virtual. With Merck. Visit here for more information.
  20. L. Zhou, J. Lomeo, S. Zhang. Linking Process & Performance of Drug Products with Micro-Image Analytics, Poster presented at: AIChE Annual Meeting, 2020 Nov 16-20; Virtual. Visit here for more information.
  21. S. Zhang, K. Nagapudi, L. Zhou, J. Lomeo. Accelerated Formulation Characterization and Development with AI Image Analysis and Image-Based Release Modeling for PLGA Implant, Poster presented at: AAPS PharmSci 360, 2020 Oct 26-Nov 5; Virtual. With Genentech. Visit here for more information.
  22. S. Zhang, Q. Bao, Y. Wang, A. Zhu. Y. Qin, D. Burgess, L. Zhou. Drug Particle Characterization Inside Long-Acting Intrauterine Systems with 3D Imaging Analytics, Poster presented at: AAPS PharmSci 360, 2020 Oct 26-Nov 5; Virtual. With the FDA and UCONN. Visit here for more information.
  23. R. Wang, Q. Bao, Y. Wang, S. Choi, L. Zhou, S. Zhang, D. Burgess. Formulation Optimization of PLGA Microspheres Prepared Using a Coacervation Method, Poster presented at: AAPS PharmSci 360, 2020 Oct 26-Nov 5; Virtual. With the FDA and UCONN. Visit here for more information.
  24. J. Lomeo, L. Zhou. Particle Analysis within Drug Products: Novel Methods in Quantification using 3D Microscopy, Poster presented at: AAPS PharmSci 360, 2020 Oct 26-Nov 5; Virtual. Visit here for more information.
  25. H. Xi, A. Zhu, G.R. Klinzing, L. Zhou, S. Zhang, A.J. Gmitter, K. Ploeger, P. Sundararajan, M. Mahjour, W. Xi. Characterization of Spray Dried Particles Through Microstructural Imaging, Journal of Pharmaceutical Sciences 109 (11) (2020) 3404-3412. DOI. With Merck. Visit here for more information.
  26. D. Wu, L. Zhou, S. Zhang. Characterization of Controlled Release Microspheres Using FIB-SEM and Image-Based Release Prediction, AAPS PharmSciTech 21 (194) (2020). DOI. With Bausch Health.
  27. S. Zhang, K. Nagapudi. Micro-imaging Based Characterization and Release Prediction of a Long-Acting PLGA Implant, Poster presented at: Long-Acting Injectables and Implantables Conference, 2020 Feb 6-7; La Jolla, CA. With Genentech.
  28. S. Zhang, J. Goldman, X. Chen, J. Rowe, S. Lin, L. Zhou. Non-Invasive, Quantitative Characterization of Lyophilized Drug Product Using Three-Dimensional X-Ray Microscopy Analytics, Drug Development & Delivery (January/February) (2020) 32-40. Online publication.
  29. L. Zhou, P, Stroud, A. Zhu, J. Hinds, K. Blakely, S. Zhang. Characterization of Spray-Dried Aggregates for Tablet Formulation with Microstructure 3D Imaging Analytics, Poster presented at: AAPS PharmSci 360, 2019 Nov 3-6; San Antonio, Texas. With Eli Lilly.
  30. L. Zhou, X. Chen, J. Goldman, J. Rowe, S. Zhang, S. Lin. Non-invasive Three-dimensional X-Ray Microscopy Imaging Technique for Quantitative Characterization of Lyophilized Drug Product, Poster presented at: AAPS PharmSci 360, 2019 Nov 3-6; San Antonio, Texas. With Bristol-Myers Squibb and Moderna. 
  31. L. Zhou, J., Lomeo S. Zhang. Drug Substance / Drug Product Characterization and Performance Prediction Using High Resolution 3D Micro-Imaging Analysis, Poster presented at: Applied Pharmaceutical Analysis, 2019 Sept 9-11; Boston, MA. Recognized as an Outstanding Poster.
  32. E. Yost, P. Chalus, S. Zhang, S. Peter, A.S. Narang. Quantitative X-Ray Microcomputed Tomography Assessment of Internal Tablet Defects, Journal of Pharmaceutical Sciences 108 (5) (2019) 1818-1830. DOI. With Genentech, Lonza, and Roche.
  33. H. Hao, K. Nagapudi, S. Zhang. Impact of method of preparation on the morphology and mechanical properties of Amorphous solid dispersion: Comparison of Co-precipitation and Spray Drying, Poster presented at: AAPS PharmSci 360, 2018 Nov 4-7; Washington, D.C. With Genentech. 
  34. M. Venters, N. Klaus E. LaChapelle, A. Pluntze, K. Pugh, M. Shaffer, S. Zhang. Focused Ion Beam Analysis of Lipid Multiparticulates. Poster presented at: AAPS PharmSci 360, 2018 Nov 4-7; Washington, D.C. With Lonza.
  35. S. Zhang, J. Neilly, A. Zhu, J. Chen, G. Danzer. Quantitative Characterization of Crystallization in Amorphous Solid Dispersion Drug Tablets Using X-Ray Micro-Computed Tomography, Microscopy & Microanalysis 24 (S1) (2018) 1400-1401. DOI. With AbbVie.
  36. D. Wu, S. Zhang. Microimaging Characterization and Release Prediction of Controlled Release Microspheres, Presented at: Controlled Release Society Annual Meeting and Exposition, 2018 Jul 22-24; New York City, NY. With OraPharma.
  37. E. Yost, P. Chalus, S. Zhang, S. Peter A.S. Narang. Quantitative X-ray Micro-Computed Tomography Assessment of Internal Tablet Defects. Presented at: Compaction Simulation Forum, 2018 Jun 11-13; San Francisco, CA. With Genentech.
  38. S. Poozesh, N. Setiawan, F. Arce, P. Sundararajan, J.D. Rocca, A. Rumondor, D. Wei, R. Wenslow, H. Xi, S. Zhang, J. Stellabott, Y. Su, J. Moser, P.J. Marsac. Understanding the process-product-performance interplay of spray dried drug-polymer systems through complete structural and chemical characterization of single spray dried particles, Powder Technology 320 (2017) 685-695. DOI.
  39. S. Zhang, Z. Liu. Correlative Microimaging and Image-Based Diffusion Simulation to Predict Extended Release Drug Performance, Invited talk at: AAPS 2017 Symposium of Assembling an Advanced Analytical Toolkit to Support LAP Dosage Forms, 2017 Nov 12-15; San Diego, CA.
  40. S. Poozesh, N. Setiawan, F. Arce, P. Sundararajan, J.D. Rocca, A. Rumondor, D. Wei, R. Wenslow, H. Xi, S. Zhang, J. Stellabott, Y. Su, J. Moser, P.J. Marsac. Understanding the Process-Product-Performance Interplay of Spray Dried Drug-Polymer Systems through Complete Structural and Chemical Characterization of Single Spray Dried Particles, Poster presented at: AAPS Annual Meeting and Exposition, 2017 Nov 12-15; San Diego, CA.
  41. S. Zhang. Correlative focused ion beam scanning electron microscope and x-ray micro-computed tomography imaging on multi-scale drug release characterization and 3D-printing manufacturing, Poster presented at: Controlled Release Society Annual Meeting, 2017 Jul 16-19; Boston, MA.
  42. Z. Liu, L. Li, S. Zhang, D. Wei, D. Skomski, R. Teller, S. Forster, C. Yen, M.A. Mackey, S.E. Barrett, Z. Yang, J. Zhang, W. Xu, M. Gindy, A. Leone. Advanced Image Characterization and Analysis on Polymer Based Implantable Dosage Formulations, Poster presented at: Controlled Release Society Annual Meeting, 2017 Jul 16-19; Boston, MA. With Merck. 
  43. S. Zhang, C. Zhang, G. Brynes, Microscopic Image Based Drug Delivery System Characterization. Poster presented at: AAPS Annual Meeting, 2016 Nov 13-17; Denver, CO.
  44. S. Zhang. DigiMedicine: FIB-SEM/MicroCT 3D imaging for drug microstructure and deliverability characterization, Presented at: AAPS National Biotechnology Conference, 2016 May 16-18; Boston, MA.
  45. S. Zhang. Advances in Solid State Imaging of Pharmaceutical Systems, Invited talk at: AAPS Arden House Conference, 2016 Apr 18-20; Baltimore, MD. With Prof. Patrick Marsac, Univ. of Kentucky.
  46. G. Bryne, J. Chen. Microstructure Investigation of Controlled Release Multi-Particulates Using FIB-SEM, Presented at: APS UKPharmSci, 2013 Sep 2-4; Edinburgh, UK. With Merck.
  47. D. Wei, S. Jacobs, S. Modla, S. Zhang, C.L. Young, R. Cirino, J. Caplan, K. Czymmek. High-resolution three-dimensional reconstruction of a whole yeast cell using focused-ion beam scanning electron microscopy, BioTechniques, 53 (1) (2012) 41-48. DOI.
  48. K. Mao. Microstructural Investigation of Tablet Compaction and Tablet Pharmacological Properties, Ph.D. Thesis, MIT, Cambridge (2010). With Novartis. Online Publication.
  1. S. Eichmann, P. Srinivasan, K. Kenga, M. Khan, F. Duque, F. Oyarzabal, J. Howard, S. Zhang. Improved Nanoscale Image-based Reservoir Characterization using Supervised Machine Learning, Paper presented at: Unconventional Resources Technology Conference, 2021 Jul 26-28; Houston, TX. With Aramco Services Company. DOI. 
  2. S. Eichmann, P. Srinivasan, S. Zhang, J. Howard. Quantitative Image Analysis of Source Rocks Using Machine Learning Segmentation, Microscopy and Microanalysis 26 (S2) (2020) 2862-2865. DOI. With Aramco Services Company.
  3. J. Howard. Machine-Learning Methods in Image Processing and Analysis of Porous Materials, DigiM Solutions Whitepaper, 2019.
  4. S. Zhang, A.P. Byrnes, J. Howard. Properties Upscaling in Porosity Systems with Under-resolved Features Using Image-Based Rock Physics, Paper presented at: Unconventional Resources Technology Conference, 2019 Jul 22-24; Denver, CO. DOI. With Whiting. 
  5. J. Howard, S. Lin, S. Zhang. Uncertainty Quantification in Image Segmentation for Image-Based Rock Physics in a Shaly Sandstone, Petrophysics 60 (2) (2019) 240-254. DOI. Visit here for more information.
  6. J. Howard, S. Lin, S. Zhang. Uncertainty Quantification in Image Segmentation for Image-based Rock Physics in a Shaly-sandstone, Proceedings of International Symposium of the Society of Core Analysts, 2018 Aug 27-30; Trondheim, Norway.
  7. A.P. Byrnes, S. Zhang, L. Canter, M.D. Sonnenfeld. Application of Integrated Core and Multiscale 3-D Image Rock Physics to Characterize Porosity, Permeability, Capillary Pressure, and Two and Three-Phase Relative Permeability in the Codell Sandstone, Denver Basin, Colorado, Paper presented at: Unconventional Resources Technology Conference, 2018 Jul 23-25; Houston, TX. With Whiting. Visit here for more information.
  8. S. Zhang, N. Ionkina. The Impact of Capillary Condensation on the Hydrocarbon Storage and Mobility, Presented at: AAPG Annual Convention & Exhibition, 2019 May 20-23; Salt Lake City, UT.
  9. S. Zhang, L. Canter, M. Sonnenfeld. Capillary Fluid Dynamics within Unconventional Rocks Investigated by Scanning Electron Microscope, AAPG Bulletin 101 (11) (2017) 1759–1765. DOI. With Whiting. 
  10. S. Rassenfoss. Need a Faster Measure of Relative Permeability? Take a CT Scan and Follow With Digital Rock Analysis, Journal of Petroleum Technology 69 (08) (2017) 28-31. DOI.
  11. A.P. Byrnes, S. Zhang, L. Canter, M.D. Sonnenfeld. Two-phase and three-phase relative permeability of unconventional Niobrara chalk using integrated core and 3D image rock physics, Presented at: Rocky Mountain Association of Geologists / Denver Well Logging Society Fall Symposium, 2017 Sept 27-28; Golden, CO. With Whiting. Visit here for more information.
  12. A.P. Brynes, S. Zhang, L. Canter, M.D. Sonnenfeld. Application of integrated core and 3D image rock physics to characterize Niobrara chalk porosity, permeability, capillary pressure, and two and three-phase relative permeability, Paper presented at: Unconventional Resources Technology Conference, 2017 July 24-26; Austin, TX. DOI. With Whiting. Visit here for more information.
  13. L. Canter, S. Zhang, M.D. Sonnenfeld, C. Bugge, M. Guisinger, K. Jones. Primary and Secondary Organic Matter Habit in Unconventional Reservoirs, in: T. Olson, AAPG Memoir 102: Imaging Unconventional Reservoir Pore Systems 112 (2016). DOI. With Whiting. 
  14. X. Jin, X. Wang, L. Sun, J. Li, X. Liu, Z. Yao, F. Meng, S. Zhang. Study of Petrophysical Properties Using Nano-Scale Resolution Electron Microscopy and 3D to 2D Upscaling, Journal of Nanoscience and Nanotechnology 16 (9) (2016) 9690-9698. DOI. With PetroChina. 
  15. J.H. Chen, B. Li, D. Georgi, J. Chen, W. Yang. Petrographic Features of Kerogen in Unconventional Shales and Their Effect on Hydrocarbon Petrophysics, Paper presented at: Abu Dhabi International Petroleum Conference & Exhibition, 2012 Nov 11-14; Abu Dhabi, UAE. DOI. With Bakerhughes. 
  16. S. Zhang, M. Pal, P. Barthelemy, M. Lei. Upscaling of Heterogeneous Rock Properties via a Multiscale Image to Simulation Approach, Presented at: COMSOL Conference, 2012 Oct 3-5; Boston, MA. With Shell.
  17. S. Zhang, R.E. Klimentidis, P. Barthelemy. Micron to millimeter upscale of shale rock properties based on 3D imaging and modeling, Paper presented at: International Symposium of the Society of Core Analysts, 2012 Aug 26-31; Aberdeen, UK. With ExxonMobil. 
  18. J.H. Chen, J. Zhang, G. Jin, T. Quinn, E. Frost, J. Chen. Capillary Condensation and NMR Relaxation Time in Unconventional Shale Hydrocarbon Resources, Paper presented at: SPWLA 53rd Annual Logging Symposium, 2012 Jun 16-20; Cartagena, Colombia. With Bakerhuges. 
  19. S. Zhang. Measurements of Porosity and permeability analysis on nanoscale FIB-SEM tomography of shale rock. Presented at: ExxonMobil Unconventional Summit, 2012 Feb 25-27; Houston, TX. With ExxonMobil and IOL Calgary. 
  20. S. Zhang. Porosity types and sizes in Shales, Measurements of Porosity and permeability analysis on nanoscale FIB-SEM tomography of mudstones, Presented at: ExxonMobil 2012 Unconventional Summit, 2012 Feb 25-27; Houston, TX. With ExxonMobil.
  21. S. Zhang, N. Saxena, P. Barthelemy, M. Marsh. Poromechanics Investigation at Pore-scale Using Digital Rock Physics Laboratory, Paper presented at: COMSOL Conference, 2011 Oct 13-15; Boston, MA. With Stanford University.
  22. S. Zhang, R.E. Klimentidis, P. Barthelemy. Porosity and permeability analysis on nanoscale FIB-SEM tomography of shale rock. Paper presented at: Society of Core Analysts Symposium, 2011 Sep 18-21; Austin, TX. With ExxonMobil.
  23. S. Zhang. Poromechanics from Volume Averaging: Lining pore-scale physics to macro-scale, Presented at: Society of Exploration Geophysicists 2011 Annual Meeting, 2011 Sep 18-23; San Antonio, TX. With Stanford University.
  24. S. Zhang. A virtual material studio to study rock petrophysical properties, Presented at: 11th International Conference on Magnetic Resonance Microscopy / Joint Topic Conference on NMR in Well Logging and Core Analysis 2011 Aug 14-18; Beijing, China. With University of Alberta.
  25. S. Zhang, F.D. Maestra, N. Combaret, R.E. Klimentidis, P. Barthelemy, R. Albou, D. Lichau. The Analysis and Simulation of Rock Properties Using FIB-SEM and Virtual Material Studio, Presented at NAFEMS World Congress, 2011 May 22-26; Boston, MA. With ExxonMobil.
  26. Brown. Analysis and Simulation of Rock Properties, Interview with Shawn Zhang in Comsol News 2011, 58-59. Read online here.
  1. Y. Suleiman, N. May, M. Zhang, A. Zhu, S. Zhang, J. McCutcheon, S. Shahbazmohamadi. In-situ 3D X-ray Tomography and Analysis of Reverse Osmosis Membranes Under Compaction. Microscopy and Microanalysis (28:S1) (2022) 270-271. DOI. 
  2. J. Tracey, S. Lin, J. Jankovic, A. Zhu, S. Zhang. Iterative Machine Learning Method for Pore-Back Artifact Mitigation in High Porosity Membrane FIB-SEM Image Segmentation, Microscopy and Microanalysis 25 (S2) (2019) 186-187. DOI.
  3. L. Zhu, D. Yin, Y. Qin, S. Konda, S. Zhang, A. Zhu, S. Liu, T. Xu, M.T. Swihart, H. Lin. Sorption‐Enhanced Mixed Matrix Membranes with Facilitated Hydrogen Transport for Hydrogen Purification and CO 2 Capture, Advanced Functional Materials 29 (36) (2019) doi:10.1002/adfm.201904357. DOI.
  4. J. Jankovic, S. Zhang, A. Putz, M.S. Saha, D. Susac. Multiscale imaging and transport modeling for fuel cell electrodes, Journal of Materials Research 34 (4) (2019) 579-591. DOI. Visit here for more information.
  5. C. Kamp, S. Zhang, G. Monahan, S. Bagi, Y. Wang. High Resolution X-ray Computed Tomography for the Measurement and Simulation of Decreased Permeability in the Wall-Flow Diesel Particulate Filter due to the Accumulation of Lubricant-Derived Ash, Poster presented at: MRS Fall Meeting, 2017 Nov 26-Dec 1; Boston, MA. With MIT.
  6. A.M.V. Putz, S. Zhang, J. Jankovic, D. Susac, J. Chen. Multi-Scale Image-Based Characterization of Electrochemical Energy Material System, Talk presented at: MRS Fall Meeting, 2017 Nov 26-Dec 1; Boston, MA. With AFCC.
  7. A.M.V. Putz, S. Zhang, J. Jankovic, D. Susac, J. Chen. Microscopy Supported Multi-Scale Modeling of PEM Fuel Cells, Presented at: Electrochemical Society Meeting, 2017 May 28-Jun 1; New Orleans, LA. With AFCC.
  8. C.J. Kamp, S. Zhang, S. Bagi, V. Wong, G. Monahan, A. Sappok, Y. Wang. Ash Permeability Determination in the Diesel Particulate Filter from Ultra-High Resolution 3D X-Ray Imaging and Image-Based Direct Numerical Simulations, SAE International Journal of Fuels and Lubricants 10 (2) (2017) 608-618. With MIT and Cummins. DOI. Visit here for more information.
  9. M. Marsh, S. Zhang P. Itty, P. Monitero. Microstructural Evolution in Concrete by In-Situ X-Ray Microtomography, Presented in: International Conference on Cement Microscopy, 2013 Apr 28-May 1; Chicago, IL.
  10.  
  1. S. Zhang. System and methods for computing drug controlled release performance using images. U.S. Patent No. 11,081,212 B2. United States Patent and Trademark Office. Filed Oct. 5, 2018. Awarded Aug. 3, 2021.
  2. S. Zhang. Managing microstructure imaging data: A call for cloud-based storage. Read more here. 
  3. P. Luner. Microstructural characterization of Amorphous Spray Dried Dispersions: A Novel Technique to Save Time in Process and Performance Decisions. Read more here.
  4. S. Zhang. System and methods for computing physical properties of materials using imaging data. U.S. Patent No. 10,830,713. United States Patent and Trademark Office. Filed Nov. 20, 2018. Awarded Nov. 10, 2020.
  5. J. Tracey, S. Lin, J. Jankovic, A. Zhu, S. Zhang. Iterative Machine Learning Method for Pore-Back Artifact Mitigation in High Porosity Membrane FIB-SEM Image Segmentation, Microscopy and Microanalysis 25 (S2) (2019) 186-187. DOI. 
  6. S. Zhang, A.P. Byrnes, J. Jankovic, J. Neilly. Management, Analysis, and Simulation of Micrographs with Cloud Computing, Microscopy Today 27 (2) (2019) 26-33. DOI. 
  7. C. Y. Zhang. Reconstruction of Three-Dimensional Micro-Structures From Two-Dimensional Microscopic Images Using Texture Synthesis and Phase Field Method, Poster presented at: Microscopy & MicroAnalysis 2019, 2019 Aug 4-8; Portland OR. 
  8. S. Zhang. DigiM Artificial Intelligence Image Processing, DigiM Technology Highlight July (2017).
  9. S. Zhang. DigiM FIB-SEM Curtaining Removal, DigiM Technology Highlight February (2015). Visit here for more information.
  10. S. Zhang. Integrated Material Characterization and Property Prediction Using 3D Image-based Analytics and Modeling, Talk presented at: TMS 2014 Annual Meeting, 2014 Feb 16-20; San Diego, CA.
  11. S. Zhang. Seminar: From 3D Microtomography to Qualitative and Quantitative Analysis, June 27-28, 2013. With Zeiss Xradia.
  12. S. Zhang. 3D Correlative Microscopy: Analysis and Modeling Challenges, Talk presented at Yale Microscopy Workshop, 2013 Jun 4; New Haven, CT. 
  13. G. Tallec, P. Westenberger, N. Combaret, S. Zhang, D. Lichau. New approaches for characterization of porous media: from segmented 3D FIB/SEM images to material properties simulation, Presented at: 5th International Conference on Porous Media & Annual Meeting, 2013 May 21-24; Prague, Czech Republic.
  14. S. Zhang. Advanced processing and modeling methods for porous material FIB-SEM data, Presented at: 6th Annual FIB SEM Workshop at Harvard University, 2013 Mar 1; Cambridge, MA.
  15. M. Lei, S. Zhang, L. Bernard, P. Barthelemy. On quantification of fibrous material. Invited Talk presented at: TMS 2013 Annual Meeting, 2013 Mar 3-7; San Antonio, TX.
  16. S. Zhang. The analysis and modeling of CT scan data at multiple scales in food, metrology and energy applications, Presented at: CT Scan Workshop Development on non-medical environment State of the Art. INRS-ETE. 2012, Mar 6-9; Quebec City, Canada.
  17. S. Zhang. Modeling and simulation based on 3D micro to nano-scale imaging, Presented at: FIB SEM User Group Meeting hosted by Carnegie Institution of Washington, 2012 Feb 14; Washington, D.C. 
  18. S. Zhang, 3D Visualization and Analysis for Material and Life Sciences, Presented at: University of Delaware Visualization Seminar, 2012 Feb 23; Newark, DE.
  19. H. Qiu, V. Stepanov, T. Chou, S. Zhang, A. Di Stasio, A. Surapaneni, W. Lee. Preparation and Characterization of an Insensitive RDX-based Nanocomposite Explosive, Talk presented at: Symposium Y: Advances in Energetic Materials Research at the Material Research Society Fall Meeting & Exhibit, 2011 Nov 26-30; Boston, MA. With Stevens Institute of Technology and US Army Research.
  20. S. Zhang. From 3D images to simulations: practical issues and software tools, Presented at: International Conference on Flows and Mechanics in Natural Porous Media from Pore to Field Scale, 2011 Nov 16-18; Rueil-Malmaison, France.
  21. S. Zhang. 3D Data Analysis Workshop, Presented at: 11th International Conference on Magnetic Resonance Microscopy / Joint Topic Conference on NMR in Well Logging and Core Analysis 2011 Aug 14-18; Beijing, China.
  22. S. Zhang. 3D visualization and quantification on Confocal microscopic and FIB/SEM data, Presented at: Stevens Institute of Technology, 2012 Jun 23; Hoboken, NJ.
  23. S. Zhang. Advanced 3D visualization and Analysis on FIB data, Presented at: DC Area FIB User Group Meeting, 2012 Feb 25; Gaithersburg, MD.
  24. S. Zhang. 3D Data Acquisition and Processing, Presented at: NIST Workshop on FIB/SEM Nanotomography; 2010 Feb 4-5; Gaithersburg, MD.
  25. S. Zhang. 3D Microscopy Data: from image space to pore space, from qualitative visualization to quantitative analysis, Invited talk presented at: Second mini-workshop on 3D imaging in microscopy, National Institute for Nanotechnology, 2010 Oct 14-15; Edmonton, Alberta.
  26. S. Zhang. Visualization Challenges in CAE, Presented at: NAFEMS Webinar Series, 2010 July 28; Virtual.
  27. D.J. Roth, R.W. Rauser, A. Abdul-Aziz, R. Cotton, E. Burke, S. Zhang, M. Marsh, B.A. Davis, G.F. Studor, Recent Improvements in Display and Analysis of NDE Data at NASA. QNDE 2010 Jul 18-23; San Diego, CA. With NASA. DOI. Visit here for more information.
  28. S. Zhang. Visualization and Analysis Solutions for Material Sciences along with RoboMet.3D, Presented at: MRSEC Summer School 2010 on Methods for 3D Microstructural Studies, Carnegie Mellon University; Pittsburgh, PA.
  29. P.S. Takhar, S. Zhang. Drying of Corn Kernels: From Experimental Images to Multi-scale Multi-physics Modeling, Presented at: COMSOL Conference, 2009 Oct 8-10; Boston, MA. With University of Illinois at Urbana-Champaign.
  30. S. Zhang, P. Barthelemey, J. Noel. Advanced 3D Data Analysis and Visualization in Aluminum Die Casting using Computed Tomography, Presented at: Materials Science & Technology Conference, 2009 Oct 25-29; Pittsburgh, PA. With North Star Imaging. 
  31. S. Zhang. 3D Material Characterization, Presented at: Material Research Society Fall Conference & Exhibition, 2008 Dec 2-4; Boston, MA.
  1. J. Lomeo, S. Zhang, P. Yawman. Digital drug formulation and design: critical insights from microstructure imaging, Talk presented at AAPS Northeast Regional Discussion Group (NERDG) 2021 Annual Meeting, 2021 Apr 16; Virtual. Visit here for more information.
  2. M. Korang-Yeboah from the FDA. Root cause analysis of an inverse relationship between the ice nucleation temperature of a controlled ice nucleation process, process performance and product attributes, Talk featuring DigiM’s analysis presented at International Forum on Process Analytical Chemistry (IFPAC) Annual Meeting, 2021 Feb 28-Mar 5; Virtual. Visit here for more information.
  3. M. Korang-Yeboah from the FDA. Root cause analysis of an inverse relationship between the ice nucleation temperature of a controlled ice nucleation process, process performance and product attributes, Talk featuring DigiM’s analysis presented at International Forum on Process Analytical Chemistry (IFPAC) Annual Meeting, 2021 Feb 28-Mar 5; Virtual. Visit here for more information
  4. S. Zhang, J. Lomeo, A. Zhu. Non-invasive 3D X-Ray microscopy imaging technique for quantitative characterization of lyophilized drug product, Talk presented at International Forum on Process Analytical Chemistry (IFPAC) Annual Meeting, 2021 Feb 28-Mar 5; Virtual. With the FDA. Visit here for more information.
  5. S. Zhang, A. Koynov, J. Lomeo. Computer Aided Drug Formulation Design with Image-Based Microstructure Modeling, Talk presented at: AIChE Annual Meeting, 2020 Nov 16-20; Virtual. With Merck. Abstract here.
  6. L. Zhou, J. Lomeo, S. Zhang. Linking Process & Performance of Drug Products with Micro-Image Analytics, Poster presented at: AIChE Annual Meeting, 2020 Nov 16-20; Virtual. Abstract here.
  7. J. Lomeo, S. Zhang. DigiM Solution Technology Workshop: Microstructure Characterization for Drug Development: Novel AI Analytics and Release Prediction. Talk presented at: AIChE Annual Meeting, 2020 Nov 16-20; Virtual.
  8. S. Zhang. Artificial-Intelligence Image Analysis of API and Microporosity in Drug Products, Talk presented at: AAPS PharmSci 360, 2020 Oct 26-Nov 5; Virtual.
  9. J. Lomeo, S. Zhang, K. Nagapudi. Characterization & Release Prediction for Long Acting Implants, Talk presented at: Controlled Release Society Annual Meeting, 2020 Jun 29-Jul 2; Virtual. With Genentech.
  10. S. Zhang. Monolithic Release Simulation, Talk presented at:Controlled Release Society Annual Meeting, 2020 Jun 29-Jul 2; Virtual.
  11. S. Zhang. Image Based Microstructure Bioequivalence Evaluation, Talk presented at FY 2020 Generic Drug Regulatory Science Initiatives Public Workshop, 2020 May 4; Virtual. News here.