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Press Releases & News
- DigiM Awarded FDA Contract to Study Microstructure Bioequivalence of Polymer-based Long-acting Drugs (in collaboration with the Diane Burgess Laboratory at UConn). Read the press release. Medical News press release available here.
- DigiM’s Quantitative Image Characterization Featured in FDA Workshop. Read the press release and watch the presentation. AZO Materials press release available here.
Recent and Upcoming Events
Pharmaceutical
- American Association of Pharmaceutical Scientists (AAPS) PharmSci 360 – Virtual Meeting – October 26-November 5
DigiM presented the following talks and posters with our collaborators:
- Rapid Fire Talk: Artificial-Intelligence Image Analysis of API and Microporosity in Drug Products. Request link.
- Accelerated Formulation Characterization and Development with AI Image Analysis and Image-Based Release Modeling for PLGA Implant. With Genentech. Abstract here.
- Drug Particle Characterization Inside Long-Acting Intrauterine Systems with 3D Imaging Analytics. With the FDA and UCONN. Abstract here.
- Formulation Optimization of PLGA Microspheres Prepared Using a Coacervation Method. With the FDA and UCONN. Abstract here.
- Particle Analysis within Drug Products: Novel Methods in Quantification using 3D Microscopy. Abstract here.
- American Institution of Chemical Engineers (AIChE) Annual Meeting – Virtual Meeting – November 16-20 DigiM presented three talks at 2020 AIChE Annual Meeting:
- Sponsored Talk Workshop: Microstructure Characterization for Drug Development: Novel AI Analytics and Release Prediction on November 17th, 12-1 PM EST. Abstract here.
- Linking Process & Performance of Drug Products with Micro-Image Analytics on November 19th, 11-12 PM EST. Abstract here.
- Computer Aided Drug Formulation Design with Image-Based Microstructure Modeling on November 20th, 11-12 PM EST. Abstract here.
- Compaction Simulation Forum (CSF) – Boston, MA – January 2021
Recent Presentations and Publications
- Zhang, S., Koynov, A., and Lomeo, J. (2020). Computer Aided Drug Formulation Design with Image-Based Microstructure Modeling. Poster presented at 2020 AIChE Annual Meeting. With Merck. Request link.
- Zhou, L., Lomeo, J., and Zhang, S. (2020). Linking Process & Performance of Drug Products with Micro-Image Analytics. Poster presented at 2020 AIChE Annual Meeting. Request link.
- Zhang, S., Nagapudi, K., Zhou, L., Lomeo, J. (2020). Accelerated Formulation Characterization and Development with AI Image Analysis and Image-Based Release Modeling for PLGA Implant. Poster presented at 2020 AAPS PharmSci 360. With Genentech. Request poster.
- Zhang, S., Bao, Q., Wang, Y., Zhu. A., Qin, Y., Burgess, D., Zhou, L. (2020). Drug Particle Characterization Inside Long-Acting Intrauterine Systems with 3D Imaging Analytics. Poster presented at 2020 AAPS PharmSci 360. With the FDA and UCONN. Request poster.
- Wang, R., Bao, Q., Wang, Y., Choi, S., Zhou, L., Zhang, S., Burgess, D. (2020). Formulation Optimization of PLGA Microspheres Prepared Using a Coacervation Method. Poster presented at 2020 AAPS PharmSci 360. With the FDA and UCONN. Request poster.
- Lomeo J., Zhou, L. (2020). Particle Analysis within Drug Products: Novel Methods in Quantification using 3D Microscopy. Poster presented at 2020 AAPS PharmSci 360. Request poster.
- Xi, H., Zhu, A., Klinzing, G.R., Zhou, L., Zhang, S., Gmitter, A.J., Ploeger, K., Sundararajan, P., Mahjour, M., Xi, W. (2020). Characterization of Spray Dried Particles Through Microstructural Imaging. Journal of Pharmaceutical Sciences.August 2020. With Merck. Request paper or manuscript.
- Wu, D., Zhou, L., Zhang, S. (2020). Characterization of Controlled Release Microspheres Using FIB-SEM and Image-Based Release Prediction. AAPS PharmSciTech. July 2020. With Bausch Health. Request paper.
- Zhang, S., Nagapudi, K. (2020). Micro-imaging Based Characterization and Release Prediction of a Long-Acting PLGA Implant. Poster presented at the Long-Acting Injectables and Implantables meeting in La Jolla, CA. With Genentech. Request poster.
- Zhang, S., Goldman, J., Chen, X., Rowe, J., Lin, S., Zhou, L. (2020). Non-Invasive, Quantitative Characterization of Lyophilized Drug Product Using Three-Dimensional X-Ray Microscopy Analytics. Drug Development & Delivery.Read full paper here.