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Press Releases & News
DigiM Awarded FDA Contract to Study Microstructure Bioequivalence of Polymer-based Long-acting Drugs (in collaboration with the Diane Burgess Laboratory at UConn). Read the press release. Medical News press release available here.
American Association of Pharmaceutical Scientists (AAPS) PharmSci 360 – Virtual Meeting – October 26-November 5
DigiM will present from 4:00-4:15 PM EST on October 29 about Artificial-Intelligence Image Analysis of API and Microporosity in Drug Products in the Manufacturing and Analytical Characterization Chemical track. Additionally, DigiM will participate in a panel discussion on October 30 from 10:30-11:30 AM EST about Artificial Intelligence/Machine Learning: An Emerging Bioanalytical Solution. Lastly, DigiM have the following poster presentations with our collaborators:
Accelerated Formulation Characterization and Development with AI Image Analysis and Image-Based Release Modeling for PLGA Implant. With Genentech. Link here.
Drug Particle Characterization Inside Long-Acting Intrauterine Systems with 3D Imaging Analytics. With the FDA and UCONN. Link here.
Formulation Optimization of PLGA Microspheres Prepared Using a Coacervation Method. With the FDA and UCONN. Link here.
Particle Analysis within Drug Products: Novel Methods in Quantification using 3D Microscopy. Link here.
Xi, H., Zhu, A., Klinzing, G.R., Zhou, L., Zhang, S., Gmitter, A.J., Ploeger, K., Sundararajan, P., Mahjour, M., Xi, W. (2020). Characterization of Spray Dried Particles Through Microstructural Imaging. Journal of Pharmaceutical Sciences.August 2020. With Merck. Request paper or manuscript.
Wu, D., Zhou, L., Zhang, S. (2020). Characterization of Controlled Release Microspheres Using FIB-SEM and Image-Based Release Prediction. AAPS PharmSciTech. July 2020. With Bausch Health. Request paper.
Zhang, S., Nagapudi, K. (2020). Micro-imaging Based Characterization and
Release Prediction of a Long-Acting PLGA Implant. Poster presented at the Long-Acting Injectables and Implantables meeting in La Jolla, CA. With Genentech. Request poster.
Zhang, S., Goldman, J., Chen, X., Rowe, J., Lin, S., Zhou, L. (2020). Non-Invasive, Quantitative Characterization of Lyophilized Drug Product Using Three-Dimensional X-Ray Microscopy Analytics. Drug Development & Delivery.Read full paper here.
Howard, J. (2019). Machine-Learning Methods in Image Processing and Analysis of Porous Materials. DigiM whitepaper. Available for request.
Zhou, L., Stroud, P., Zhu, A., Hinds, J., Blakely, K., Zhang, S. (2019). Characterization of Spray-Dried Aggregates for Tablet Formulation with Microstructure 3D Imaging Analytics. Poster presented at AAPS PharmSci 360 2019 in San Antonio, Texas. With Eli Lilly. Request poster.
Zhu, L., Yin, D., Qin, Y., Konda, S., Zhang, S., Zhu, A., . . . Lin, H. (2019). Sorption‐Enhanced Mixed Matrix Membranes with Facilitated Hydrogen Transport for Hydrogen Purification and CO2 Capture. Advanced Functional Materials.Read abstract. Request manuscript.
Howard, J., Lin, S., & Zhang, S. (2019). Uncertainty Quantification in Image Segmentation for Image-Based Rock Physics in a Shaly Sandstone. Petrophysics,60(2), 240-254. Read abstract. Request the manuscript.