digiM AAPS Topical and Transdermal Community 2024

Formulation development and optimization of topical dosage forms often involves some guesswork with selecting formulation and process parameters. Globule characterization can play a pivotal role in offering insights for innovators and generic formulators during the development lifecycle of topical products. Globules within topical products can be achieved through the use of high-resolution 3D X-ray micro-CT, with AI analysis enabling the inspection of products in their native states.

Key Learning Objectives:

• What globule attributes can we quantify with non-invasive analysis?
• How can we assess Q3 bioequivalence for topical products?
• How can these CQAs accelerate process and formulation selection?